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Egteghdeghi ec oXir
Hr. Lragndsni Jigzacez Iteri
Hra. Agjecdna @erez
Mispdtac Ugdversdtardi he Naranas
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Egteghdeghi ec oXir
Hr. Lragndsni Jigzacez Iteri
Hra. Agjcdna @erez
Mispdtac Ugdversdtardi he Naranas
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oaooacdag tarjet il rapaoyndgEc bcagni he ca rapaodndga eg cis oaoleris
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oXIR es uga serdga/treigdga ndgasa, rejucahira negtrac hec
nrendodegti, hdleregndandg, pricdlerandg, odjrandg y
supervdvegnda necucar.
^u antdvdhah est rejucaha pir ca nignegtrandg he aodgindhis, AXV,
jcunisa y pir lantires he nrendodegti y sus reneptires.
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\a RXK -VD>KAktoXIR
lislatdhdcdgisdtic->-qudgasa (VD>K)
reneptir tdrisdga qudgasa
. Ca rejucandg pir cis lantires he nrendodegti es tragsodtdha pir ca va hec lantir he nrendodegt
sdodcar a ca dgsucdga-lislatdhdc-dgisdtic-> ndgasa AKX-oXIR (DJLR-VD>K-AKX-oXIR), uga nasnaha h
pritegas ndgasas que estdouca ca lugndg he oXIR
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Ca mdperantdvandg he ca seac oehdaha pir oXIR est recandigaha nig
ec hesarricci, ec nrendodegti y ca pricdlerandg he masta ec 56% he cis
ngneres muoagis.
Outandiges eg ca va VD>K-AKX-oXIR se mag recandigahi nig
1. Dghunndg he ca tragsliroandg oacdjga necucar
2. Hesrejucandg he ca pricdlerandg yca qudodiresdstegnda
>. Xuoirijgesds
8. Geiagjdijgesds
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Ca antdvandg he oXIR es rejucaha gejatdvaoegte pir X^N1/2 (niopce`i he ca esncerisdstuberisa) y VXEG (miociji he lislatasa y tegsdga eg hecendg eg ec nrioisioa 16).
Hahi que estis jeges supresires tuoiraces sulreg uga outandg lrenuegte eg ec
ngner, ca lugndg he oXIR est auoegtaha y cas ncucas tuoiraces sigmdpersegsdbces a cis agtajigdstas he oXIR.
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Landac agjdildbrioas ir liremeah pcaque
Gigtrauoatdn ugjuac ir perdugjuac ldbrioa
Mypioecagitdn oanuce (tmree ir oire)
^majreeg patnm (niggentdve tdssue gevus) Ouctdpce retdgac gihucar maoartioas
Nirtdnac tuber
^ubepeghyoac gihuce
^ubepeghyoac jdagt necc astrinytioa
Narhdan rmabhioyioa, sdgjce ir ouctdpce
Cyopmagjdioyioatisds
Regac agjdioyicdpioa
Niopce`i Esncerisds Xuberisa
Nrdterdis Oayires
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Ouctdpce, raghiocy hdstrdbuteh pdts dg hegtac egaoec
Maoartioatius rentac picyps
Bige nysts
Nerebrac wmdte oatter rahdac odjratdig cdges
Jdgjdvac ldbrioas
Gigregac maoartioas
Retdgac anmriodn patnm Niglettd skdg cesdigs
Ouctdpce regac nysts
Niopce`i Esncerisds Xuberisa
Nrdterdis Oegires
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Niopce`i Esncerisds Xuberisa
2 Nrdterdis oayires 1 Nrdterdi oayir
+
2 Nrdterdis oegires
Hdajgstdni Heldgdtdvi0
1 Nrdterdi oayir
+
1 Nrdterdi oegir
Hdajgstdni Vribabce0
1 Nrdterdi oayir
7 2 Nrdterdis oegires
Hdajgstdni Visdbce0
Y
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Ca esncerisds tuberisa (EX) es uga
jegiheroatisds he meregnda autisodnahiodgagte y expresdvdhah vardabce que se
naranterdza pir ca liroandg ouctdsdstodna he
tuoirandIges maoartioatisas.
Cis jeges supresires tuoiraces X^N1
Jeges ^upresires Xuoiraces X^N1 T X^N2
Nihdldnag Vritegas Maoartdga y Xuberdga
Liroag Niopce`i
Dgmdbe oXir
Vritega Lughaoegtac Eg Ca Rejucandg He Ca Vricdlerandg T
Hdleregndandg Necucar.
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Auoegti eg ca dgndhegnda he XGEs, Vagnretdni ( dgsucdgioa)
X^N1 / X^N2 jeges supresires tuoiraces dgvicunrahis eg ca va he oXIR
Ca outandg autisodna hiodgagte he cis jeges X^N1 i X^N2
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Dgmdbdhir hec oXIR.
Vrevegndg hec renmazi he rjagis
1. Anndg dgougisupresira
2. Antdvdhah agtdtuoirac se basa eg ca giroacdzandg he
ca seacdzandg he ca va hec oXIR
>. Antdvdhah agtdagjdijgdna ac hdsodgudr cis gdveces he
lantir he nrendodegti eghitecdac vasnucar
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Evericdous, Xeosdricdous, Rdhaliricdous
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Respigsabce 0 outandg eg ec jeg GL-1 que privina uga antdvandg he ca va he oXIR a travs
he ug oenagdsoi hepeghdegte he RA^ y VD>K
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Esncerisds
tuberisa
Oacliroandiges vasnucares
Jcdibcastioa
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\a oXIR .
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Ahrdegge O. Maoodcc, OH, VmH, Oary^ue Zegtzec, RG, Agdta Jupta, OH, ^tepmeg
Gecsig, OH, Agge Cunky, OH, Ravd Eccuru, OH, VmH, Rismgd Hasjupta, OH, Rdnmarh J.
Azdzkmag, OH, agh Hegdse O. Ahaos, OH
Vehdatr Bciih Nagner 2611;5:0161=1628
^dricdous lir tme Xreatoegt il
Niopcdnateh \asnucar
Agioacdes dg Nmdchreg
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Bankjriugh. \asnucar agioacdes nioprdse a hdverse jriup il hdajgises. Zmdce
dglagtdce meoagjdioas are niooig, tme oa`irdty il tmese nighdtdigs are qudte rare agh
mave git beeg wdhecy stuhdeh.
^ioe il tmese cesdigs, tmiujm begdjg, nag dopadr vdtac struntures, be helirodgj, ir eveg
benioe cdle-tmreategdgj. \asnucar tuoirs sunm as kapisdliro meoagjdieghitmecdioas
(KME) agh niopcdnateh vasnucar oacliroatdigs mave priveg partdnucarcy hdlldnuct ti treat.
Vrinehure. Mere we retrispentdvecy evacuate a serdes il sdx patdegts wdtm niopcdnateh,
cdle-tmreategdgj vasnucar agioacdes wmi were treateh wdtm tme oXIR dgmdbdtir sdricdous
lir niopassdigate use at twi negters alter ladcdgj ouctdpce itmer tmerapdes.
Resucts. Xmese patdegts smiweh sdjgdldnagt dopriveoegt dg ncdgdnac status wdtm ticerabce
sdhe ellents.
Nigncusdigs. ^dricdous appears ti be ellentdve agh sale dg patdegts wdtm cdle-tmreategdgj
vasnucar agioacdes agh represegts ag dopirtagt tiic dg treatdgj tmese hdseases. Xmese
ldghdgjs are nurregtcy bedgj lurtmer evacuateh dg a Vmase DD saletyagh elldnany trdac.
^dricdous lir tme Xreatoegt il Niopcdnateh \asnucar Agioacdes dg
Nmdchreg
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DGXERGAXDIGAC ^INDEXT LIR XME ^XUHT IL \A^NUCAR AGIOACDE^
(D^^\A)
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oXIR .
^erdge/tmreigdge kdgase
Rejucaha pir pmispmidgisdtdhe->-kdgase (VD>K)
Outandiges eg cis supresires he tuoires X^N1 y X^N2
NEX y CAO
Vricdlerandg Necucar y Agjdijegesds
^dricdous y itris dgmdbdhires oXIR
Vricdl Necc Agjdijegesds
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\a oXIR .
Itris Odeobris \a 0 VD>K/oXIR
Liroandg y Vripajandg he Agioacas \asnucares
\asnucar eghitmecdac jriwtm lantir (\EJL)0 rejucahir cdglagjdijgesds y agjdijgesds
Akt 0 ^ibre expresahi eg Nec. eghitecdaces nec oacliroandiges vasnucar nutgeas
Outandiges dg VXEG 0 agioacas vasnucares lcu`i rpdhi y lcu`i cegti y nrendodegti exnesdvi
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Hisds Dgdndac 0 6.= oj/o2 hisds bdh
A`uste eg gveces 0 1615 gj/oc.
Vrildcaxds Vgeuoinystds 0 Nitrdoixazice Vegtaodhdge
Vrioehdi Respuesta 0 25 h. (= a
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^dricdous lir tme Xreatoegt il Niopcdnateh \asnucar
Agioacdes dg Nmdchreg
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Hisds Dgdndac 0 6.= oj/o2 hisds bdh
A`uste eg gveces 0 1615 gj/oc.
Vrildcaxds Vgeuoinystds 0 Nitrdoixazice Vegtaodhdge
Vrioehdi Respuesta 0 25 h. (= a
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^dricdous lir tme Xreatoegt il Niopcdnateh \asnucar
Agioacdes dg Nmdchreg
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Ounisdtds
Mdpernicestericeoda
Nelacea
Ecevandig he A^X / ACX
Geutripegda
Respdratiry ^ygnytdac \drus (R^\) e Dglcuegza A
Xmese patdegts smiweh ticerabce sdhe ellents.
^dricdous lir tme Xreatoegt il Niopcdnateh \asnucar
Agioacdes dg Nmdchreg. Elentis ^enughardis
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Nmest ]-rays smiw tme status il tme patdegtsellusdigs dg (A) prdir ti startdgj sdricdous, agh dg (B) 2
oigtms cater.
Vmitis smiw tme appearagne il mds cyopmatdn cesdig, wdtm vdsdbce skdg dgvicveoegt, prdir ti sdricdous dg(N) agh severac oigtms cater dg (H).
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Xuoires \asnucares y Oacliroandg Cdgltdna
Niopigegte Cdgltdni
Dgmdbe Cdglagjdijgesds
Exnecegte Respuesta
Elentis ^enughardis Xicerabces
Oenagdsoi agtdagjdijgdni/agtdpricdleratdvi
Oacliroandiges 0 Estabces y Gi Vricdleratdvas.
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Ounisdtds
Mdpernicestericeoda
Nelacea
Ecevandig he A^X / ACX
Geutripegda
Respdratiry ^ygnytdac \drus (R^\) e Dglcuegza A
Xmese patdegts smiweh ticerabce sdhe ellents.
^dricdous lir tme Xreatoegt il Niopcdnateh \asnucar
Agioacdes dg Nmdchreg. Elentis ^enughardis
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1. Xrataodegti ^ecentdvi
2. Anndg Dgougisupresira
>. Antdvdhah Agtdtuoirac
8. Antdvdhah Agtdagjdijgdna
5. Niopce`i Esncerisds Xuberisa
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