7/25/2019 Mecanismos Contraccin Del Musculo a Nivel de Las Miofibrillas

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ANATOFISIOLOGA DEL MSCULO ESQUELTICOFIBRA MUSCULAR:La fbra muscular s u!a c"lula muscular# s $us%$&rm ' mul(%!uclar) La mmbra!a clular sllama*a sarc&lma ' l c%(&+lasma s llama*& sarc&+lasma) C&!(%! &r,a!l&s clulars# !-cl&clular# m%&,l&b%!a ' u! c&m+l.& !(rama*& +r&(%c& * fbras llama*as ac(%!a ' m%&s%!a cu'a+r%!c%+al +r&+%*a*# llama*a c&!(rac(%l%*a*# s la * ac&r(ar su l&!,%(u* cua!*& s&! s&m(%*as au! s(/mul& 0u/m%c& & l"c(r%c&)

MIOFIBRILLA:Es u!a s(ruc(ura c&!(r1c(%l 0u a(ra2%sa las c"lulas *l (.%*& muscular# ' ls *a la +r&+%*a* *c&!(racc%3! ' * las(%c%*a*# la cual +rm%( ral%4ar l&s m&2%m%!(&s carac(r/s(%c&s *l m-scul&)Ca*a fbra muscular c&!(%! 2ar%&s c%!(&s & m%llars * m%&fbr%llas) Ca*a m%&fbr%lla c&!(%!m%&flam!(&s c&! u!&s 5677 flam!(&s * m%&s%!a ' 8777 flam!(&s * ac(%!a) Es(as s&!m&l"culas * +r&(/!a +&l%mr%4a*as ' a las cuals ls c&rrs+&!* l +a+l * la c&!(racc%3!)Las m%&fbr%llas s(1! sus+!*%*as *!(r& * la fbra muscular ! u!a ma(r%4 *!&m%!a*asarc&+lasma)

SARCOMERO: El sarc3mr& s la u!%*a* a!a(3m%ca ' $u!c%&!al *l m-scul $&rma*& * ac(%!a '

m%&s%!a) La c&!(racc%3! *l m-scul& c&!s%s( ! l *sl%4am%!(& * l&s m%&flam!(&s * ac(%!as&br l&s m%&flam!(&s * m%&s%!a) E! l sarc3mr& +u*! *%s(%!,u%rs l&s flam!(&s * ac(%!a9flam!(& f!& 0u !ac! * l&s *%sc&s ;# *&!*

7/25/2019 Mecanismos Contraccin Del Musculo a Nivel de Las Miofibrillas

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>l%c&%*als !r&lla*as !(r s/) La (r&+&!%!a: r&(/!a ,l&bular 0u s *%s+&! s&br la m&l"cula* ac(%!a) Ea * +r&*uc%rs u!a c&!(racc%3!# *a!*&lu,ar a la $u!c%3! * la Tr&+&m%&s%!a)&r l& 0u rs+c(a a la m&l"cula * AT# "s(a c&!s(%(u' !s/ m%sma l rsr2&r%& +ara l almac!am%!(& * la !r,/a !csar%a +ara 0u s ll2 a cab& lac&!(racc%3! muscular)

U!a 24 0u l flam!(& * Ac(%!a s(1 $/s%cam!( *%s+us(& +ara !(rar ! c&!(ac(& c&! l

flam!(& * M%&s%!a# ' +&r $c(& * la +rs!c%a * u! %3! * ma,!s%& ! s( flam!( s*s+r!* * la m&l"cula * AT u!& * sus (rs $&s$a(&s# l cual s ca+(a*& +&r la Cra(%!%!a) As/l AT s c&!2%r( ! u!a m&l"cula * A*!&s%!D%$&s$a(& 9u! !lac * ?a*!&s%!? c&! *&sm&l"culas * $&s$a(& & AD# m%!(ras la Cra(%!%!a# m1s l $&s$a(& 0u ca+(3 s c&!2%r( !F&s$&cra(%!a & C) C&! *%c>& *s+r!*%m%!( la !r,/a 0u/m%ca almac!a*a ! la m&l"cula *AT s c&!2%r( ! la !r,/a mc1!%ca 0u >ac 0u s mu2a la cab4a *l flam!(& *M%&s%!a# .ala!*& a la Ac(%!a# ' 2&l2%!*& %!m*%a(am!( *s+u"s a su +&s%c%3! &r%,%!al) Es!(&!cs la F&s$&cra(%!a 9C racc%&!a a!( la +rs!c%a * la !4%ma C ' l%bra su $&s$a(*&!1!*&l& a la m&l"cula * AD# la cual s c&!2%r( !u2am!( ! AT# ' 0u*a l%s(a +ara u!

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!u2& c%cl& ! l 0u sa m%sma cab4a * M%&s%!a c&!(r%bu%r1 a la c&!(racc%3! * u! m-scul&)&r su +ar(# la C 'a u(%l%4a*a# s 2a al (&rr!( sa!,u/! * *&!* lu,& sr1 l%m%!a*a) H%s(&*s* u! +&c& m1s l.&s# l +r&cs& * c&!(racc%3!rla.ac%3! * u! m-scul& !& s &(ra c&sa 0ul (raba.& 0u ral%4a la M%&s%!a al .alar ' s&l(ar l flam!(& * Ac(%!a)

Al f!al# s(a >%s(&r%a *.a clar& 0u la -!%ca $u!c%3! * la C s la ca(1l%s%s * la F&s$&cra(%!a+ara 0u "s(a *&! su $&s$a(& a la m&l"cula * AD# c&!2%r(%"!*&la ! AT# ' >ac%!*& * "s(a u!

!u2& rsr2&r%& * !r,/a 0u/m%ca# l%s(a +ara sr c&!2r(%*a ! la !r,/a mc1!%ca !csar%a+ara l +r&cs& * c&!(racc%3! *l m-scul&)D a0u/ s %!fr claram!( 0u# cua!*& ral%4am&s u! s$ur4& $/s%c cual0u%ra 0u sa su!a(ural4a ' su %!(!s%*a*# ! la sa!,r s +u* !c&!(rar c%r(a ca!(%*a* * C) E! &(ras+alabras# ' *a*& 0u la 2%*a m%sma %m+l%ca l m&2%m%!(& c&!s(a!( * m-scul&s# (a!(& *a0ull&s 0u *+!*! * !us(ra 2&lu!(a* 9l&s * !us(r&s bra4&s & +%r!as# +&r .m+l c&m&l&s 0u s&! c&!(r&la*&s +&r !us(r& S%s(ma Nr2%&s& Au(3!&m& 9c&ra43!# +ulm&!s# (c)# s *s+rars 0u ! !us(ra sa!,r s%m+r a !4%ma)