Presentation9 Types Nosocom

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    Nosocomial InfectionsDr. A. A. Wegdan

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    1- Surgical site infection (SSI) Classification

    A - Superficial incision SSI. Infection occurs within 30 days.

    It involves skin or SC tissue.

    B - Deep incision SSI. Infection occurs 30 days after the operation, or 1 year with implant.

    It involves deep soft tissues.

    C - Organ/Space SSI. Infection occurs 30 days after the operation, or 1 year with implant.

    Infection involves organs/spaces component.

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    1- Surgical site infection (SSI)

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    1- Surgical site infection (SSI)

    Manifestations and Diagnosis

    - Superficial incision SSI.1- Purulent drainage, with or without laboratory confirmation.

    2- Organisms isolated.

    3- At least one of: pain or tenderness, swelling, redness, or heat and incision

    opened by surgeon.

    4- Clinical diagnosis.

    - Deep incision SSI.

    1- Purulent drainage from the deep incision, not from the organ/ space.2- Spontaneous dehisces or open & the patient has at least one of: fever,

    pain, tenderness.

    3- An abscess.

    4- Surgeon confirmation.

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    1- Surgical site infection (SSI)

    - Organ/Space SSI.1- Purulent drainage.

    2- Organisms isolated.

    3- An abscess or other evidence of infection.

    4- Diagnosis by surgeon or attending physician.

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    2. Urinary tract infections (UTI)

    Classification and manifestations

    - Asymptomatic bacteriuria. Patient has no symptoms (No fever or dysuria or frequency).

    - Symptomatic UTI: (with or without history of

    catheterization).

    Patient has one of the following symptoms:

    - Fever > 38 C.

    - Urgency.

    - Dysuria or supra pubic pain.

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    2. Urinary tract infections (UTI)

    Diagnosis

    - Asymptomatic bacteriuria.

    Patient has history of urinary catheter (7 days) and a positive urine

    culture of >105 microorganism/ml

    Or he has two positive urine cultures of > 105 microorganism/ml of

    the same organisms.

    - Symptomatic UTI (with or without history of

    catheterization).

    Patient has positive urine culture(>105 microorganism/ml, with nomore than two isolated microorganism).

    Or he has Positive urine culture > 103 microorganism/ml and positive

    leucocyturia of > 104 l /ml.

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    3. Respiratory tract infection (RTI)

    Classification

    - Upper respiratory infections (nose, throat, ear).

    - Lower respiratory infections (pneumonia).

    Manifestation and Diagnosis- Lower respiratory infections (pneumonia).

    a. Clinical (Signs/symptoms):

    i. Patient has at least one of the following:

    1. Recent fever >38.5oC with no other cause.

    2. Leucopenia or leucocytosis.

    3. Patient is >70 years old, has altered mental status with no other

    cause.

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    3. Respiratory tract infection (RTI)

    Manifestation and Diagnosis

    - Lower respiratory infections (pneumonia).

    ii. And with at least 2 of the following:-

    1. New onset of purulent sputum or change in character or

    respiratory secretions.

    2. New onset or worth of cough or dyspnea or tacpnea.

    3. Worse gas exchange.

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    3. Respiratory tract infection (RTI)

    b. Diagnostic radiology:

    Patient shows in two or more serial X-ray at least one of :

    1. New or progressive and persistent Infiltrate.

    2. Consolidation.

    3. Cavitations.

    4. Pneumatocele (infants < 1 year).

    c. Laboratory evidence:

    1. Positive growth in blood culture (with x-ray and clinical).

    2. Positive growth in expectorate with an organism never commensal:

    Legionel la, As pergi l lus.

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    4. Intravascular catheter related

    infections Classification

    # Local

    - Catheter colonization.

    - Phlebitis.

    - Exit site infection (within 2 cm).

    # Blood stream infection (Bacteremia)

    Primary.

    Secodary (CRI): In patient with I.V.C.

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    4. Intravascular catheter related

    infections Manifestation and Diagnosis

    # Local

    Induration and/or erythema along S.C. tract of catheter.

    Signs of inflammation.

    Exudation/Purulent fluid at catheter site exit.

    By culture of catheter tip.

    # Blood stream infection (Bacteremia)

    Fever > 38C.

    Chills.

    Hypotension.

    One positive blood culture from peripheral blood culture.

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    4. Intravascular catheter related

    infections Prevention

    a. Peripheral catheter:

    - Minimize patient exposure to peripheral catheterization.

    - That could be through:

    Insertion only if necessary.

    Early removal if not used.

    Maximum duration for an adult is< 96 h.

    Daily inspection of the insertion site and immediateremoval if infection is suspected.

    Hand disinfection before insertion.

    Skin disinfection before insertion.

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    4. Intravascular catheter related

    infections

    b. Central Venous Catheter:

    A written protocol for using CVC.

    The indications of insertion/duration of CVC be limited.

    Continuous education of health-care workers.

    The protocol should contain information about:

    - Precautions for insertion:

    Surgical conditions (sterile mask, cap, gowns and gloves), large sterile

    drapes

    Skin disinfection

    Limit the use of the venous line

    Insertion sites

    - subclavian (if more than 5-7 days), jugular, femoral.

    - tunneling of CVC for jugular or femoral site.

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    4. Intravascular catheter related

    infections- Type of catheter:

    Polyurethane, silicone (better than Teflon or PVC)

    Mono-lumen = multi-lumen

    Coated catheters

    - With silver chlorhexidine-sulfadiazine: possible.- With heparin: less thrombosis.

    - Use in aseptic conditions

    Daily clinical surveillance.

    No scheduled systematic replacement.

    Wound dressing- Date placement, date refection.

    - Occlusive dressing (replaced every 72 h).

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    4. Intravascular catheter related

    infections

    - Replacement of the lines Optimum 2 to 3 days.

    Except if blood transfusion or lipid perfusion (change/day)

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    5. Gastrointestinal infection

    Classification

    # Gastroentritis/Food poisoning.

    - Acute onset of diarrhea with / without vomiting.

    # Hepatitis

    - Jaundice.

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    5. Gastrointestinal infection

    Manifestation and Diagnosis

    # Gastroentritis/Food poisoning: Two of:

    Nausea and vomiting.

    Ab dominal pain.

    Headache.

    Any laboratory evidence of enteric pathogens.

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    5. Gastrointestinal infection

    # Hepatitis: Two of: Fever > 38.

    Anorexia.

    Nausea.

    Vomiting.

    Abdominal pain.

    Jaundice.

    Or history of transfusion (3 months).

    Laboratory confirmation: Positive laboratory tests for hepatitis viruses.

    Abnormal liver function tests.

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    6. Systemic infections Viral etiology.

    Many organs are involved.

    Diagnosed only clinically.

    Examples: Mumps, rubella, varicella.

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